(4R,12aS)-9-Bromo-3,4,12,12a-tetrahydro-4-methyl-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-d2-6,8-dione

CAS: 1206102-10-4

Ref. TR-B688272

Información del producto

• Nombre: (4R,12aS)-9-Bromo-3,4,12,12a-tetrahydro-4-methyl-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-d2-6,8-dione
• Sinónimos: (3S,7R)-13-bromo-5,5-dideuterio-7-methyl-11-phenylmethoxy-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-9,12-dione
• Marca: TRC
• Descripción: Applications (4R,12aS)-9-Bromo-3,4,12,12a-tetrahydro-4-methyl-7-(phenylmethoxy)-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-d2-6,8-dione is an isotope labelled intermediate of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor.

Propiedades químicas

• Peso molecular: 421.281
• Fórmula: C₁₉D₂H₁₇BrN₂O₄
• Color/Forma: Neat
• InChI: InChI=1S/C19H19BrN2O4/c1-12-7-8-25-15-10-21-9-14(20)17(23)18(16(21)19(24)22(12)15)26-11-13-5-3-2-4-6-13/h2-6,9,12,15H,7-8,10-11H2,1H3/t12-,15+/m1/s1/i8D2
• Clave InChI: InChIKey=XKXSSMSOAWHOLM-IBQUEKPOSA-N
• SMILES: [2H]C1([2H])C[C@@H](C)N2C(=O)c3c(OCc4ccccc4)c(=O)c(Br)cn3C[C@@H]2O1