8-Bromo-2’,3’,5’-tri-O-acetylguanosine-13C2,15N

CAS: 15717-45-0

Ref. TR-B688327

Información del producto

• Nombre: 8-Bromo-2’,3’,5’-tri-O-acetylguanosine-13C2,15N
• Sinónimos: 8-Bromo-guanosine 2',3',5'-Triacetate-13C2,15N, 2',3',5'-Tri-O-acetyl-8-bromoguanosine-13C2,15N, NSC 174056-13C2,15N, NSC 79210-13C2,15N, 2',3',5'-tri-O-acetyl-8-bromoguanosine, 2-amino-8-bromo-9-(2,3,5-tri-O-acetylpentofuranosyl)-3,9-dihydro-6H-purin-6-one, 2′,3′,5′-Tri-O-acetyl-8-bromoguanosine, 8-Bromo-2′,3′,5′-tri-O-acetylguanosine, 8-Bromoguanosine 2',3',5'-triacetate, 8-Bromoguanosine 2′,3′,5′-triacetate, Guanosine, 8-bromo-, 2′,3′,5′-triacetate, NSC 174056, NSC 79210

Descripción

Applications 8-Bromo-2’,3’,5’-tri-O-acetylguanosine-13C2,15N is an intermediate in the synthesis of 8-Aminoguanosine-13C2,15N (A609877). 8-Aminoguanosine-13C2,15N is an isotopic labelled compound of 8-Aminoguanosine (A609875), which is a potent inhibitor of purine nucleoside phosphorylase. 8-Bromo-2’,3’,5’-tri-O-acetylguanosine-13C2,15N is also a labelled analog of 8-Bromo-2’,3’,5’-tri-O-acetylguanosine (B688325).
References Kazmers, I.S., et al.: Science, 214, 1137 (1981); Chern, J-W., et al.: J. Med. Chem., 36, 1024 (1993)

• Marca: TRC

Propiedades químicas

• Peso molecular: 491.226
• Fórmula: C₂C₁₄H₁₈BrNN₄O₈
• Color/Forma: Neat
• InChI: InChI=1S/C16H18BrN5O8/c1-5(23)27-4-8-10(28-6(2)24)11(29-7(3)25)14(30-8)22-12-9(19-15(22)17)13(26)21-16(18)20-12/h8,10-11,14H,4H2,1-3H3,(H3,18,20,21,26)/t8-,10-,11-,14-/m1/s1/i9+1,12+1,19+1
• Clave InChI: InChIKey=JLZCAXCVNVVXJL-FZXKLGSOSA-N
• SMILES: CC(=O)OC[C@H]1O[C@@H](n2c(Br)[15n][13c]3c(=O)[nH]c(N)n[13c]32)[C@H](OC(C)=O)[C@@H]1OC(C)=O