Buserelin Acetate

CAS: 57982-77-1 59179-42-9 68630-75-1

Ref. TR-B689740

Información del producto

• Nombre: Buserelin Acetate
• Sinónimos: 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-1-9-Luteinizing hormone-releasing factor (swine) acetate (1:1), 1-9-Luteinizing hormone-releasing factor (swine), 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-, monoacetate (salt) (9CI), Luteinizing hormone-releasing factor (pig), 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-10-deglycinamide-, monoacetate (salt), 1-9-Luteinizing hormone-releasing factor (pig), 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-, monoacetate (salt), Conceptal, Estomal, Gonaxal, Sprecur MP, Suprafact, Suprecur, Supremon
• CAS: 57982-77-1 59179-42-9 68630-75-1

Descripción

Stability Hygroscopic
Applications Gondadotropin-releasing hormone agonist, used to treat hormone-responsive cancers such as prostate and breast cancer. Synthetic nonapeptide agonist analog of LH-RH. Antineolpastic (hormonal).
References Lam, P., et al.: Gynecol. Endocrinol., 24, 674 (2008), Chi, K., et al.: J. Urol., 180, 565 (2008), Menchaca, A., et al.: Theriogenol., 72, 477 (2009), Harada, T., et al.: Fertility and Sterility, 91, 675 (2009),

• Marca: TRC

Propiedades químicas

• Peso molecular: 1299.48
• Fórmula: C₆₀H₈₆N₁₆O₁₃•x(CH₄O₂)
• Color/Forma: White to Off-White Solid
• InChI: InChI=1S/C60H86N16O13.C2H4O2/c1-7-64-57(87)48-15-11-23-76(48)58(88)41(14-10-22-65-59(61)62)69-51(81)42(24-33(2)3)70-56(86)47(31-89-60(4,5)6)75-52(82)43(25-34-16-18-37(78)19-17-34)71-55(85)46(30-77)74-53(83)44(26-35-28-66-39-13-9-8-12-38(35)39)72-54(84)45(27-36-29-63-32-67-36)73-50(80)40-20-21-49(79)68-40, /m0./s1, 1H3,(H,3,4)/t40-,41-,42-,43-,44-,45-,46-,47+,48-, 1-2(3)4/h8-9,12-13,16-19,28-29,32-33,40-48,66,77-78H,7,10-11,14-15,20-27,30-31H2,1-6H3,(H,63,67)(H,64,87)(H,68,79)(H,69,81)(H,70,86)(H,71,85)(H,72,84)(H,73,80)(H,74,83)(H,75,82)(H4,61,62,65)
• Clave InChI: InChIKey=PYMDEDHDQYLBRT-DRIHCAFSSA-N
• SMILES: CC(=O)O.CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](COC(C)(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCC(=O)N1