5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione

CAS: 830346-48-0

Ref. TR-B750323

Información del producto

• Nombre: 5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione
• Sinónimos: 5-Bromo-1-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-6-methyl-2,4(1H,3H)-pyrimidinedione, 1-[2-Fluoro-6-(trifluoromethyl)benzyl]-5-bromo-6-methyl-1H-pyrimidine-2,4-dione, 5-bromo-1-(2-fluoro-6-(trifluoromethyl)benzyl)-4-hydroxy-6-methylpyrimidin-2(1H)-one
• CAS: 830346-48-0

Descripción

Applications 5-Bromo-1-[2-Fluoro-6-(trifluoromethyl)benzyl]-6-methylpyrimidine-2,4(1H,3H)-dione is an intermediate in the synthesis of Elagolix, a gonadotropin-releasing hormone antagonist (GnRH) used in the treatment of endometriosis.
References Tukun, F. et al.: Molecules, 22, 12 (2017);

• Marca: TRC

Propiedades químicas

• Peso molecular: 381.12
• Fórmula: C₁₃H₉BrF₄N₂O₂
• Color/Forma: Neat
• InChI: InChI=1S/C13H9BrF4N2O2/c1-6-10(14)11(21)19-12(22)20(6)5-7-8(13(16,17)18)3-2-4-9(7)15/h2-4H,5H2,1H3,(H,19,21,22)
• Clave InChI: InChIKey=RDQPTRWUBKZZFJ-UHFFFAOYSA-N
• SMILES: Cc1c(Br)c(=O)[nH]c(=O)n1Cc1c(F)cccc1C(F)(F)F