Canagliflozin Hydrate

CAS: 1869942-80-2

Ref. TR-C175259

Información del producto

• Nombre: Canagliflozin Hydrate
• Sinónimos: (1S)-1,5-Anhydro-1-C-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol Hydrate (1:?)
• CAS: 1869942-80-2

Descripción

Stability Hygroscopic
Applications Canagliflozin Hydrate is a derivative of Canagliflozin (C175190), which is a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity.
References Chao, E. et al.: Drug Fut., 36, 351 (2011); Sha, S. et al.: Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S.: Clin. Invest., 1, 145 (2011)

• Marca: TRC

Propiedades químicas

• Peso molecular: 444.52 + x(18.02)
• Fórmula: C₂₄H₂₅FO₅S•xH₂O)
• Color/Forma: White to Off-White Solid