Carbonochloridic Acid 1,2,2,2-Tetrachloroethyl Ester

CAS: 98015-53-3

Ref. TR-C176645

Información del producto

• Nombre: Carbonochloridic Acid 1,2,2,2-Tetrachloroethyl Ester
• Sinónimos: Chloroformic Acid 11,2,2,2-Tetrachloroethyl Ester, 1,2,2,2-Tetrachloroethyl Carbonochloridate, 1,2,2,2-Tetrachloroethyl Chloroformate, (1R)-1,2,2,2-Tetrachloroethyl chloroformate, 1,2,2,2,Tetrachloroethyl chloroformate, 1,2,2,2-Tetrachloroethyl carbonochloridate, Carbonochloridic acid, 1,2,2,2-tetrachloroethyl ester, Formic acid, chloro-, 1,2,2,2-tetrachloroethyl ester

Descripción

Applications Carbonochloridic Acid 1,2,2,2-Tetrachloroethyl Ester is used in the synthesis of Doxorubicin (D558000), is used as an antineoplastic. Also used in the synthesis of metabolites of Docetaxel (D494420), a semisynthetic derivative of Paclitaxel. An antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antine oplastic.
References Di Marco, A., et al.: Cancer Chemother. Rep., (part 1), 53, 33 (1969), Mihich, E. and Ehrke, M.J.: Transplant. Proc., 16, 499 (1984); Ringel, I., et al.: J. Natl. Cancer Inst., 83, 288 (1991), Extra, J.-M., et al.: Cancer Res., 53, 1037 (1993)

• Marca: TRC

Propiedades químicas

• Peso molecular: 246.304
• Fórmula: C₃HCl₅O₂
• Color/Forma: Neat
• InChI: InChI=1S/C3HCl5O2/c4-1(3(6,7)8)10-2(5)9/h1H
• Clave InChI: InChIKey=RINXZIYBNVEZRT-UHFFFAOYSA-N
• SMILES: O=C(Cl)OC(Cl)C(Cl)(Cl)Cl