(3S)-3-[4-[(2-Chloro-phenyl)methyl]phenoxy]tetrahydrofuran

CAS: 2517968-35-1

Ref. TR-C350608

Información del producto

• Nombre: (3S)-3-[4-[(2-Chloro-phenyl)methyl]phenoxy]tetrahydrofuran
• Sinónimos: (S)-3-(4-(2-Chlorobenzyl)phenoxy)tetrahydrofuran
• Marca: TRC

Descripción

Applications (3S)-3-[4-[(2-Chloro-phenyl)methyl]phenoxy]tetrahydrofuran is an impurity in the synthesis of Empagliflozin drug (E521510), which is potent and selective inhibitor of sodium glucose co-transporter-2 (SGLT-2).
References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);

Propiedades químicas

• Peso molecular: 288.77
• Fórmula: C₁₇H₁₇ClO₂
• Color/Forma: Neat
• InChI: InChI=1S/C17H17ClO2/c18-17-4-2-1-3-14(17)11-13-5-7-15(8-6-13)20-16-9-10-19-12-16/h1-8,16H,9-12H2/t16-/m0/s1
• Clave InChI: InChIKey=JYZBRIZBJDEAIX-INIZCTEOSA-N
• SMILES: Clc1ccccc1Cc1ccc(O[C@H]2CCOC2)cc1