5-Chloro-4-(3-pyridinyl)-2-pyrimidinamine

CAS: 1900716-17-7

Ref. TR-C376016

Información del producto

• Nombre: 5-Chloro-4-(3-pyridinyl)-2-pyrimidinamine
• Sinónimos: 5-chloro-4-pyridin-3-ylpyrimidin-2-amine
• Marca: TRC
• Descripción: Applications 5-Chloro-4-(3-pyridinyl)-2-pyrimidinamine is an intermediate in the synthesis of 3-((5-Chloro-4-(pyridin-3-yl)pyrimidin-2-yl)amino)-4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)benzamide (C179120), an impurity of Nilotinib (N465300), which might be useful in treatment of chronic myelogenous leukemia.References Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),

Propiedades químicas

• Peso molecular: 206.63
• Fórmula: C₉H₇ClN₄
• Color/Forma: Neat
• InChI: InChI=1S/C9H7ClN4/c10-7-5-13-9(11)14-8(7)6-2-1-3-12-4-6/h1-5H,(H2,11,13,14)
• Clave InChI: InChIKey=WSIXNFZXJAABLD-UHFFFAOYSA-N
• SMILES: Nc1ncc(Cl)c(-c2cccnc2)n1