(1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol

CAS: 1354945-69-9

Ref. TR-C380695

Información del producto

• Nombre: (1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
• Sinónimos: (1S,2S,3R,5S)-3-[7-Chloro-5-(propylsulfanyl)[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
• Marca: TRC

Descripción

Applications (1S,2S,3R,5S)-3-[7-Chloro-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol is an intermediate in the synthesis of metaboltes of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel.

Propiedades químicas

• Peso molecular: 389.86
• Fórmula: C₁₄H₂₀ClN₅O₄S
• Color/Forma: Neat
• InChI: InChI=1S/C14H20ClN5O4S/c1-2-5-25-14-16-12(15)9-13(17-14)20(19-18-9)7-6-8(24-4-3-21)11(23)10(7)22/h7-8,10-11,21-23H,2-6H2,1H3/t7-,8+,10+,11-/m1/s1
• Clave InChI: InChIKey=OPHFHASJVWECNO-MKHNBGRSSA-N
• SMILES: CCCSc1nc(Cl)c2nnn([C@@H]3C[C@H](OCCO)[C@H](O)[C@@H]3O)c2n1