1-Chloro-1-desmethylpiperazinyl-bosutinib

CAS: 380844-49-5

Ref. TR-C423040

Información del producto

• Nombre: 1-Chloro-1-desmethylpiperazinyl-bosutinib
• Sinónimos: 7-(3-Chloropropoxy)-4-((2,4-dichloro-5-methoxyphenyl)amino)-6-methoxyquinoline-3-carbonitrile
• Marca: TRC
• Descripción: Applications 1-Chloro-1-desmethylpiperazinyl-bosutinib is a useful intermediate in the green preparation of the anti-tumor agent Bosutinib (B676095). It is a COVID19-related research product.References Mao, Y., et al.: Synthesis, 47, 3133 (2015); Chen, H., et al.: Zhongguo Yiyao Gongye Zazhi, 44, 1086 (2013); Yin, X. J., et al.: Molecules, 4261 (2010)

Propiedades químicas

• Peso molecular: 466.74
• Fórmula: C₂₁H₁₈Cl₃N₃O₃
• Color/Forma: Neat
• InChI: InChI=1S/C21H18Cl3N3O3/c1-28-18-9-17(14(23)7-15(18)24)27-21-12(10-25)11-26-16-8-20(30-5-3-4-22)19(29-2)6-13(16)21/h6-9,11H,3-5H2,1-2H3,(H,26,27)
• SMILES: COc1cc(Nc2c(C#N)cnc3cc(OCCCCl)c(OC)cc23)c(Cl)cc1Cl