4-((4-(7-Chloroquinolin-4-yl)piperazin-1-yl)sulfonyl)-3-nitroaniline

CAS: 1624602-30-7

Ref. TR-C430340

Información del producto

• Nombre: 4-((4-(7-Chloroquinolin-4-yl)piperazin-1-yl)sulfonyl)-3-nitroaniline
• Sinónimos: VR23 Relative Compound
• Marca: TRC

Descripción

Applications 4-((4-(7-Chloroquinolin-4-yl)piperazin-1-yl)sulfonyl)-3-nitroaniline is a VR23 (V767023) related compound. VR23 is a quinoline-sulfonyl hybrid proteasome inhibitor which is used in cancer therapeutics. Targets cancer via cycline E-mediated centrosome.
References Pundir, S. et al.: Canc. Res., 75, 4164 (2015);

Propiedades químicas

• Peso molecular: 447.9
• Fórmula: C₁₉H₁₈ClN₅O₄S
• Color/Forma: Neat
• InChI: InChI=1S/C19H18ClN5O4S/c20-13-1-3-15-16(11-13)22-6-5-17(15)23-7-9-24(10-8-23)30(28,29)19-4-2-14(21)12-18(19)25(26)27/h1-6,11-12H,7-10,21H2
• Clave InChI: InChIKey=SWXHLFXNQKIDJL-UHFFFAOYSA-N
• SMILES: Nc1ccc(S(=O)(=O)N2CCN(c3ccnc4cc(Cl)ccc34)CC2)c([N+](=O)[O-])c1