5-Chloro-2,3-dihydro-2-oxo-1H-indole-1-carboxylic Acid Ethyl Ester

CAS: 197776-07-1

Ref. TR-C433053

Información del producto

• Nombre: 5-Chloro-2,3-dihydro-2-oxo-1H-indole-1-carboxylic Acid Ethyl Ester
• Sinónimos: Ethyl 5-Chloro-2-oxoindoline-1-carboxylate

Descripción

Applications 5-Chloro-2,3-dihydro-2-oxo-1H-indole-1-carboxylic Acid Ethyl Ester is an intermediate used in synthesizing 2-Cyclobutenyl-3-trifluoromethyl-5-chloro-1H-indole-1-carboxylic Acid Ethyl Ester, which is synthesized from 5-chloro-2-oxindole (C375030), that is used in the preparation of novel GSK-3β inhibitors as anticancer agents.
References Choi, M.J., et al.: Bull. Korean. Chem. Soc., 32, 2015 (2011); Otani, M., et al.: Bioorg. Med. Chem. Lett.. 20, 4259 (2010); Jhan, Y.H., et al.: Tetrahedron. Lett., 54, 1155 (2013); Hsieh, J.C., et al.: Org. Biomolec. Chem., 10, 6404 (2012);

• Marca: TRC

Propiedades químicas

• Peso molecular: 239.66
• Fórmula: C₁₁H₁₀ClNO₃
• Color/Forma: Brown Solid
• InChI: InChI=1S/C11H10ClNO3/c1-2-16-11(15)13-9-4-3-8(12)5-7(9)6-10(13)14/h3-5H,2,6H2,1H3
• Clave InChI: InChIKey=CISWMYIMMKQBSJ-UHFFFAOYSA-N
• SMILES: CCOC(=O)N1C(=O)Cc2cc(Cl)ccc21