beta-Cortol

CAS: 667-65-2

Ref. TR-C696295

Información del producto

• Nombre: beta-Cortol
• Sinónimos: Pregnane-3,11,17,20,21-pentol, (3a,5ß,11ß,20R)-, 5ß-Pregnane-3a,11ß,17,20ß,21-pentol (7CI,8CI), (3a,5ß,11ß,20R)-Pregnane-3,11,17,20,21-pentol, 20ß-Cortol, 3a,11ß,17,20ß,21-Pentahydroxypregnane, 5ß-Pregnan-3a,11ß,20,20ß,21-pentol, 5ß-Pregnane-3a,11ß,17a,20ß,21-pentol, Cortol-20ß, NSC 58792, Pregnane-3a,11ß,17,20ß,21-pentol, ß-Cortol, (3alpha,5beta,11beta,20R)-pregnane-3,11,17,20,21-pentol, (3α,5β,11β,20R)-Pregnane-3,11,17,20,21-pentol, 20β-Cortol, 3α,11β,17,20β,21-Pentahydroxypregnane, 5-Beta-Pregnane-3-Alpha,11-Beta,17-Alpha,20-Beta,21-Pentaol, 5β-Pregnan-3α,11β,20,20β,21-pentol, 5β-Pregnane-3α,11β,17,20β,21-pentol, 5β-Pregnane-3α,11β,17α,20β,21-pentol, Beta-Cortol, Cortol-20β, Pregnane-3,11,17,20,21-pentol, (3α,5β,11β,20R)-, Pregnane-3α,11β,17,20β,21-pentol

Descripción

Stability Hygroscopic
Applications β-Cortol is a metabolite of cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism.
References Pasqualini, J.R., et. al.: J. Eur. Steroids, 1, 63 (1966); Vigore, L., et al.: Cancer Ther., 6, 699 (2008); Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009); Lemos, D., et al.: J. Endocrinol., 201, 275 (2009); Chen, S., et al.: Am. J. Physiol., 296 (2009)

• Marca: TRC

Propiedades químicas

• Peso molecular: 368.5
• Fórmula: C₂₁H₃₆O₅
• Color/Forma: Neat
• InChI: InChI=1S/C21H36O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-18,22-26H,3-11H2,1-2H3/t12-,13-,14+,15+,16+,17-,18-,19+,20+,21+/m1/s1
• Clave InChI: InChIKey=FFPUNPBUZDTHJI-ZFOKFBPFSA-N
• SMILES: C[C@]12CC[C@@H](O)C[C@H]1CC[C@@H]1[C@@H]2[C@@H](O)C[C@@]2(C)[C@H]1CC[C@]2(O)[C@H](O)CO