2-Cyanophenylboronic Acid

CAS: 138642-62-3

Ref. TR-C982005

Información del producto

• Nombre: 2-Cyanophenylboronic Acid
• Sinónimos: 2-Cyanobenzeneboronic Acid, [m-Cyanophenyl-4-yl]boronic acid, B-(2-Cyanophenyl)boronic Acid, 2-Cyanobenzeneboronic acid, 2-Cyanophenylboronic acid, B-(2-Cyanophenyl)boronic acid, Boronic acid, (2-cyanophenyl)-, Boronic acid, B-(2-cyanophenyl)-

Descripción

Applications 2-Cyanophenylboronic Acid is used in the synthesis of pyridine inhibitors of TAK1. Also participates in the discovery and synthesis of 1,2,4-triazoles as novel allosteric valosine containing protein (VCP) inhibitors. VCP is found highly abundant in various tumor types allowing for a potential target in cancer therapy.
References Hornberger, K. et al.: Bioorg. Med. Chem. Lett., 23, 4517 (2013); Polucci, P. et al.: J. Med. Chem., 56, 3492 (2013);

• Marca: TRC

Propiedades químicas

• Peso molecular: 146.94
• Fórmula: C₇H₆BNO₂
• Color/Forma: White to Off-White Solid
• InChI: InChI=1S/C7H9BO2/c1-6-4-2-3-5-7(6)8(9)10/h2-5,9-10H,1H3
• Clave InChI: InChIKey=NSJVYHOPHZMZPN-UHFFFAOYSA-N
• SMILES: N#Cc1ccccc1B(O)O