4-Cyanopyridine

CAS: 100-48-1

Ref. TR-C982225

Información del producto

• Nombre: 4-Cyanopyridine
• Sinónimos: 4-Pyridinecarbonitrile, Isonicotinonitrile (6CI,8CI), 4-Azabenzonitrile, 4-Pyridinenitrile, 4-Pyridyl cyanide, 4-Pyridylcarbonitrile, Isonicotinic acid nitrile, NSC 60681, γ-Cyanopyridine
• Marca: TRC

Descripción

Applications 4-Cyanopyridine is a reagent for the synthesis of 1-tolyl-5-benzylthiotetrazole and 2-hexylthio-4-pyridinecarbonitrile, an antituberculotics. Preparation of the antihypertensive agent Pinacidil using the chemoselective and green oxidative rearrangement of an amidine and addition of an amine to a guanidine as the key step. Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking. Human L-xylulose reductase (XR) is an enzyme of the glucuronic acid/uronate cycle of glucose metabolism with the possible target for treatment of the long-term complications of diabetes.
References Waisser, K., et al.: Folia Pharmaceutica Universitatis Carolinae, 18, 31 (1995); Carbone, V., et al.: Bioorg. Med. Chem., 13, 301 (2004); Baeten, M., et al.: Adv. Synth. Catal., 358, 826 (2016)

Propiedades químicas

• Peso molecular: 104.11
• Fórmula: C₆H₄N₂
• Color/Forma: Neat
• InChI: InChI=1S/C6H4N2/c7-5-6-1-3-8-4-2-6/h1-4H
• Clave InChI: InChIKey=QGZKDVFQNNGYKY-UHFFFAOYSA-N
• SMILES: N#Cc1ccncc1