Cyclophosphamide-d4

CAS: 173547-45-0

Ref. TR-C988582

Información del producto

• Nombre: Cyclophosphamide-d4
• Sinónimos: N,N-Bis(2-chloroethyl)tetrahydro-4,5-d2-2H-1,3,2-oxazaphosphorin-2-amine 2-Oxide, Cycloblastin-d4,Cyclostin-d4,Cytoxan-d4, Endoxan-d4, Genoxal-d4, Hexadrin-d4, Mitoxan-d4,NSC 26271-d4, Cycloblastin-d4, Cyclostin-d4, Cytoxan-d4, Mitoxan-d4, N,N-bis(2-chloroethyl)(4,4,5,5-2H4)-1,3,2-oxazaphosphinan-2-amine 2-oxide

Descripción

Applications It is a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. This substance is listed as a known human carcinogen.This compound is suitable for aldehyde dehydrogenase (ALDH) related research.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wheeler, A.G., et al.: Toxicol. Appl. Pharmacol., 4, 324 (1962), Fraiser, L.H., et al.: Drugs, 42, 781 (1991), Colvin, O.M., et al.: Curr. Pharmaceut. Design, 5, 555 (1999),

• Marca: TRC

Propiedades químicas

• Peso molecular: 265.11
• Fórmula: C₇H₄H₁₁Cl₂N₂O₂P
• Color/Forma: Off-White
• InChI: InChI=1S/C7H15Cl2N2O2P/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14/h1-7H2,(H,10,12)/i1D2,4D2
• Clave InChI: InChIKey=CMSMOCZEIVJLDB-RUKOHJPDSA-N
• SMILES: [2H]C1([2H])COP(=O)(N(CCCl)CCCl)NC1([2H])[2H]