[5a,7a(S)]-17-(Cyclopropylmethyl)-a-(1,1-dimethylethyl)-4,5-epoxy-3,6-dimethoxy-a-methyl-6,14-ethenomorphinan-7-methanol

CAS: 155203-04-6

Ref. TR-C989085

Información del producto

• Nombre: [5a,7a(S)]-17-(Cyclopropylmethyl)-a-(1,1-dimethylethyl)-4,5-epoxy-3,6-dimethoxy-a-methyl-6,14-ethenomorphinan-7-methanol
• Sinónimos: (alphaS,5alpha,7alpha)-17-(Cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-3,6-dimethoxy-alpha-methyl-6,14-ethenomorphinan-7-methanol

Descripción

Applications [5α,7α(S)]-17-(Cyclopropylmethyl)-α-(1,1-dimethylethyl)-4,5-epoxy-3,6-dimethoxy-α-methyl-6,14-ethenomorphinan-7-methanol is an intermediate in the synthesis of 18,19-Dehydrobuprenorphine (D229310), an analogue of Buprenorphine (B689570).
References Schutz, J., et al.: Heterocycles, 54, 989 (2001);

• Marca: TRC

Propiedades químicas

• Peso molecular: 479.65
• Fórmula: C₃₀H₄₁NO₄
• Color/Forma: Neat
• InChI: InChI=1S/C30H41NO4/c1-26(2,3)27(4,32)21-16-28-11-12-30(21,34-6)25-29(28)13-14-31(17-18-7-8-18)22(28)15-19-9-10-20(33-5)24(35-25)23(19)29/h9-12,18,21-22,25,32H,7-8,13-17H2,1-6H3/t21-,22-,25-,27?,28-,29+,30-/m1/s1
• Clave InChI: InChIKey=DLUDPCGPVOYSMR-IOMUPEQESA-N
• SMILES: COc1ccc2c3c1O[C@@H]1[C@]34CCN(CC3CC3)[C@H](C2)[C@]42C=C[C@@]1(OC)[C@@H](C(C)(O)C(C)(C)C)C2