Información del producto
- N-[S-(Dimethylarsino)-N-L-?-glutamyl-L-cysteinyl]-glycine
- Dimethylarsinic Glutathione
- ZIO 101
- Zinapar
- L-?-Glutamyl-S-(dimethylarsino)-L-cysteinyl-glycine
- <span class="text-smallcaps">L</smallcap>-γ-Glutamyl-S-(dimethylarsino)-<smallcap>L</span>-cysteinylglycine
- DMS(III)G,SGLU1,ZIO-101,Zinapar
- Dimethylarsinic glutathione
- Glycine, <span class="text-smallcaps">L</smallcap>-γ-glutamyl-S-(dimethylarsino)-<smallcap>L</span>-cysteinyl-
- Glycine, N-[S-(dimethylarsino)-N-<span class="text-smallcaps">L</smallcap>-γ-glutamyl-<smallcap>L</span>-cysteinyl]-
- Ver más sinónimos
- Zio 101
- Glycine, N-[S-(dimethylarsino)-N-L-γ-glutamyl-L-cysteinyl]-
- Glycine, L-γ-glutamyl-S-(dimethylarsino)-L-cysteinyl-
- L-γ-Glutamyl-S-(dimethylarsino)-L-cysteinylglycine
Applications Darinaparsin is an arsenic cytotoxin that has been used in pharmacological activities to evaluate the effect on survival an radiosensitivity of tumor cells in vitro under normoxia and hypoxia and in vivo using xenograft models. Darinaparsin has significant and preferential cytotoxic and radiosensitizing effects on solid tumors as compared with normal cells. Darinaparsin may therefore increase the therapeutic index of radiation therapy and has near term translational potential.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Tian, J., et al.: Clin. Cancer Res., 18, 3366 (2012); Ning, S., et al.: Int. J. Radiat. Oncol. Biol. Phys., 65, 493 (2006);
Propiedades químicas
Consulta técnica sobre: TR-D193425 Darinaparsin
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