3-​Deoxyaconitine

CAS: 3175-95-9

Ref. TR-D231553

Información del producto

• Nombre: 3-​Deoxyaconitine
• Sinónimos: [(1S,2R,3R,4R,5R,6S,7S,8R,9R,10S,13S,16S,17R,18R)-8-acetoxy-11-ethyl-5,7-dihydroxy-6,16,18-trimethoxy-13-(methoxymethyl)-11-azahexacyclo[7.7.2.12,5.01,10.03,8.013,17]nonadecan-4-yl] benzoate, 3-Deoxyaconitine, Aconitane-8,13,14,15-tetrol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, 8-acetate 14-benzoate, (1α,6α,14α,15α,16β)-, Deoxyaconitine, Deoxyaconitine, 3-

Descripción

Applications 3-​Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus blocking the nerve action potential which, in turn, blocks the release of neurotransmitters and decreases the end plate potential at the neuromuscular junction.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Derbre, S., et al.: Anal. Bioanal. Chem., 398, 1747 (2010), Li, M., et al.: J. Pharm. Biomed. Anal., 53, 1063 (2010),

• Marca: TRC

Propiedades químicas

• Peso molecular: 276.322
• Fórmula: C₃₄H₄₇NO₁₀
• Color/Forma: Neat
• InChI: InChI=1S/C34H47NO10/c1-7-35-16-31(17-40-3)14-13-21(41-4)33-20-15-32(39)28(44-30(38)19-11-9-8-10-12-19)22(20)34(45-18(2)36,27(37)29(32)43-6)23(26(33)35)24(42-5)25(31)33/h8-12,20-29,37,39H,7,13-17H2,1-6H3/t20-,21+,22-,23+,24+,25-,26+,27+,28-,29+,31+,32-,33+,34-/m1/s1
• Clave InChI: InChIKey=DNXHEGUUPJUMQT-MLDSYZRVSA-N
• SMILES: [13CH3][13C@]12CC[C@@H]3c4ccc(O)cc4CC[C@H]3[13C@@H]1[13CH2][13CH2][13C]2=O