3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib

CAS: 1603814-04-5

Ref. TR-D289540

Información del producto

• Nombre: 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib
• Sinónimos: 4-Quinazolinamine, N-(4-chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-, Gefitinib Imp. B (EP), N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine, N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine
• Marca: TRC
• Descripción: Applications 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib is an impurity of Gefitinib (G304000); a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR).References Lynch, T.J., et al.: N. Engl. J. Med., 350, 2129 (2004); Engelman, J.A., et al.: Science, 316, 1039 (2007); Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003)

Propiedades químicas

• Peso molecular: 446.90
• Fórmula: C₂₂H₂₄ClFN₄O₃
• Color/Forma: Neat
• InChI: InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-17(23)18(24)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)
• Clave InChI: InChIKey=WTDLLXPLBLPTEP-UHFFFAOYSA-N
• SMILES: COc1cc2ncnc(Nc3ccc(Cl)c(F)c3)c2cc1OCCCN1CCOCC1