2’-Des(1-hydroxy-1-methylethyl)-2’-methycarboxy Montelukast

CAS: 851755-56-1

Ref. TR-D290040

Información del producto

• Nombre: 2’-Des(1-hydroxy-1-methylethyl)-2’-methycarboxy Montelukast
• Sinónimos: 2-[(3R)-3-[[[1-(Carboxymethyl)cyclopropyl]methyl]thio]-3-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]propyl]-benzoic acid 1-methyl ester, (R)-2-[1-[[[1-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(methoxycarbonyl)phenyl]propyl]thio]methyl]cyclopropyl]acetic acid, 2-[1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-(2-methoxycarbonylphenyl)propyl]thio]methyl]cyclopropyl]acetic acid, 2-[1-[[[(1R)-1-[3-[(1E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(methoxycarbonyl)phenyl]propyl]sulfanyl]methyl]cyclopropyl]acetic acid, Montelukast Sodium Imp. H (EP)

Descripción

Impurity Montelukast EP Impurity H
Applications 2’-Des(1-hydroxy-1-methylethyl)-2’-methycarboxy Montelukast (Montelukast EP Impurity H) is an impurity of the selective leukotriene D4-receptor antagonist, Montelukast (M568000).
References Kumar, I.V. et al.: Asian J. Chem., 23, 4536 (2011);

• Marca: TRC

Propiedades químicas

• Peso molecular: 586.14
• Fórmula: C₃₄H₃₂ClNO₄S
• Color/Forma: Yellow
• InChI: InChI=1S/C34H32ClNO4S/c1-40-33(39)29-8-3-2-6-24(29)12-16-31(41-22-34(17-18-34)21-32(37)38)26-7-4-5-23(19-26)9-14-28-15-11-25-10-13-27(35)20-30(25)36-28/h2-11,13-15,19-20,31H,12,16-18,21-22H2,1H3,(H,37,38)/b14-9+/t31-/m1/s1
• Clave InChI: InChIKey=FVMXWBDOMBDOJN-JLBZDQGGSA-N
• SMILES: COC(=O)c1ccccc1CC[C@@H](SCC1(CC(=O)O)CC1)c1cccc(/C=C/c2ccc3ccc(Cl)cc3n2)c1