Desthiazolylmethyl Ritonavir

CAS: 256328-82-2

Ref. TR-D297450

Información del producto

• Nombre: Desthiazolylmethyl Ritonavir
• Sinónimos: Butanamide, 3-methyl-2-[[[methyl[[2-(1-methylethyl)-4-thiazolyl]methyl]amino]carbonyl]amino]-N-[(1S)-1-[[(4S,5S)-2-oxo-4-(phenylmethyl)-5-oxazolidinyl]methyl]-2-phenylethyl]-, (2S)-, Ritonavir Imp. L (EP), (4S,5S)-4-Benzyl-5-[(2S)-2-[[(2S)-3-methyl-2-[[methyl[[2-(1-methylethyl)thiazol-4-yl]methyl]carbamoyl]-amino]butanoyl]amino]-3-phenylpropyl]oxazolidin-2-one

Descripción

Impurity Ritonavir EP Impurity L
Applications Desthiazolylmethyl Ritonavir (Ritonavir EP Impurity L) is an analogue of the selective HIV protease inhibitor Ritonavir (R535000). It is a COVID19-related research product.
References Brittain, H., et al.: Pharm. Res., 8, 963 (1991), Sham, H., et al.: J. Med. Chem., 39, 392 (1996), Phadnis, N., et al.: J. Pharm. Sci.,86, 1256 (1997), Bauer, J., et al.: Pharma. Res., 18, 859 (2001),

• Marca: TRC

Propiedades químicas

• Peso molecular: 605.79
• Fórmula: C₃₃H₄₃N₅O₄S
• Color/Forma: Neat
• InChI: InChI=1S/C33H43N5O4S/c1-21(2)29(37-32(40)38(5)19-26-20-43-31(35-26)22(3)4)30(39)34-25(16-23-12-8-6-9-13-23)18-28-27(36-33(41)42-28)17-24-14-10-7-11-15-24/h6-15,20-22,25,27-29H,16-19H2,1-5H3,(H,34,39)(H,36,41)(H,37,40)/t25-,27-,28-,29-/m0/s1
• Clave InChI: InChIKey=YIFUFODEQQNFLV-GPGCVKFGSA-N
• SMILES: CC(C)c1nc(CN(C)C(=O)NC(C(=O)N[C@@H](Cc2ccccc2)C[C@@H]2OC(=O)N[C@H]2Cc2ccccc2)C(C)C)cs1