Diethylaminocarboxymethyl POC Tenofovir (Mixture of Diastereomers)

CAS: 1246812-23-6

Ref. TR-D443590

Información del producto

• Nombre: Diethylaminocarboxymethyl POC Tenofovir (Mixture of Diastereomers)
• Sinónimos: [[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(diethylcarbamoyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate
• Marca: TRC
• Descripción: Applications Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor. It is used as an anti-HIV agent. Antiviral. Tenofovir (T018500) impurity.References Shaw, J.-P., et al.: Pharm. Res., 14, 1824 (1997); Wyles, D., et al.: Clin Infect. Dis., 40, 174 (2005), Peng, J., et al.: J. Clin. Pharmacol., 46, 265 (2006), Seminari, E., et al.: J. Antimicrob. Chemother., 60, 831 (2007)

Propiedades químicas

• Peso molecular: 532.48
• Fórmula: C₂₀H₃₃N₆O₉P
• Color/Forma: Neat
• InChI: InChI=1S/C20H33N6O9P/c1-6-25(7-2)19(27)30-11-33-36(29,34-12-31-20(28)35-14(3)4)13-32-15(5)8-26-10-24-16-17(21)22-9-23-18(16)26/h9-10,14-15H,6-8,11-13H2,1-5H3,(H2,21,22,23)/t15-,36?/m1/s1
• Clave InChI: InChIKey=DHSVZKCBBOAHJM-DRVJNONPSA-N
• SMILES: CCN(CC)C(=O)OCOP(=O)(CO[C@H](C)Cn1cnc2c(N)ncnc21)OCOC(=O)OC(C)C