(1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate

CAS: 376608-71-8

Ref. TR-D446035

Información del producto

• Nombre: (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine (2R)-Hydroxy(phenyl)ethanoate
• Sinónimos: Benzeneacetic acid, α-hydroxy-, (αR)-(1R,2S)-compd. with 2-(3,4-difluorophenyl)cyclopropanamine (1:1), Benzeneacetic acid, α-hydroxy-, (αR)-, compd. with (1R,2S)-2-(3,4-difluorophenyl)cyclopropanamine (1:1) (9CI), (1R,2S)-2-(3,4-Difluorophenyl)cyclopropan-1-amine (R)-mandelate
• Marca: TRC
• Descripción: Applications (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine is an intermediate in the preparation of orally active reversible P2Y12 receptor antagonists such as Ticagrelor (T437700)for the prevention of thrombosis.References Springthorpe, B. et al.: Bioorg. Med. Chem. Lett., 17, 6013 (2007)

Propiedades químicas

• Peso molecular: 321.32
• Fórmula: C₉H₉F₂N·C₈H₈O₃
• Color/Forma: Neat
• InChI: InChI=1S/C9H9F2N.C8H8O3/c10-7-2-1-5(3-8(7)11)6-4-9(6)12;9-7(8(10)11)6-4-2-1-3-5-6/h1-3,6,9H,4,12H2;1-5,7,9H,(H,10,11)/t6-,9+;7-/m01/s1
• Clave InChI: InChIKey=XKAABIQBASHVGG-JYBVLTNNSA-N
• SMILES: N[C@@H]1C[C@H]1c1ccc(F)c(F)c1.O=C(O)C(=O)O.c1ccccc1