Información del producto
Nombre:
7,8-Dihydroxyflavone
Sinónimos:
- 7,8-Dihydroxy-2-phenyl-4H-chromen-4-one
- 7,8-Dihydroxy-2-phenyl-4H-1-benzopyran-4-one
- 4H-1-Benzopyran-4-one, 7,8-dihydroxy-2-phenyl-
- 7,8-Dihydroxy-2-phenyl-4-benzopyrone
- 7,8-Dihydroxy-flavone
- 7,8-dihydroxy-2-phenyl-4H-chromen-4-one
- Brn 0234350
- Flavone, 7,8-dihydroxy-
Descripción:
Applications 7,8-Dihydroxyflavone is disubstituted flavone that acts as a small-molecule TrkB agonist. 7,8-Dihydroxyflavone has been shown to reverse memory deficits and BACE1 elevation in a mouse model of Alzheimer's disease. 7,8-Dihydroxyflavone may also provide a therapeutic option in the treatment of other neorological disorders such as Rett syndrome and PTSD. It has recently been shown to counteract the inhibition of NMDA receptor caused by lead poisoning and confer protective effects in live rats.
References Devi, L. et al.: Neuropsychopharmacology, 37, 434 (2012); Andero, R. et al.: Hippocampus, 22, 399 (2012); Johnson, R.A. et al.: J. Appl. Physiol., 112, 704 (2012); Chem. and Eng. News Nov. 20, 2017, page 5
Aviso:
Nuestros productos están destinados únicamente para uso en laboratorio. Para cualquier otro uso, por favor contáctenos.
Marca:
TRC
Almacenamiento de larga duración:
Notas:
Propiedades químicas
Peso molecular:
254.24
Fórmula:
C15H10O4
Color/Forma:
Pale Yellow to Yellow Solid
InChI:
InChI=1S/C15H10O4/c16-11-7-6-10-12(17)8-13(19-15(10)14(11)18)9-4-2-1-3-5-9/h1-8,16,18H
Clave InChI:
InChIKey=COCYGNDCWFKTMF-UHFFFAOYSA-N
SMILES:
O=c1cc(-c2ccccc2)oc2c(O)c(O)ccc12
MDL:
Punto de fusión:
Punto de ebullición:
Punto de inflamabilidad:
Densidad:
Concentración:
EINECS:
Merck:
Código HS:
