2,4-Dinitrophenyl 2-Deoxy-2-fluoro-beta-D-galactoside

CAS: 143716-62-5

Ref. TR-D480065

Información del producto

• Nombre: 2,4-Dinitrophenyl 2-Deoxy-2-fluoro-beta-D-galactoside
• Sinónimos: 2,4-Dinitrophenyl 2-Deoxy-2-fluoro-β-D-galactopyranoside, 2',4'-Dinitrophenyl 2-deoxy-2-fluoro-beta-D-galactopyranoside, Dinitroph-dfgp, beta-D-Galactopyranoside, 2,4-dinitrophenyl 2-deoxy-2-fluoro-, 2',4'-Dinitrophenyl 2-deoxy-2-fluorogalactopyranoside

Descripción

Applications Fluorinated and deoxygenated glycosides as mechanistic probes of Escherichia coli (lacZ) β-galactosidase. By use of the slow substrate 2,4-dinitrophenyl-2-deoxy-2-fluoro-β-D-galactopyranoside, a glycosyl enzyme intermediate has been trapped on the enzyme. Glu-268 was identified as the catalytic nucleophile of human lysosomal β-galactosidase precursor.
References Withers, S., et al.: J. Biol. Chem., 263, 7929 (1988), D'Agrosa, R., et al.: Biochem. J., 285, 833 (1992),

• Marca: TRC

Propiedades químicas

• Peso molecular: 348.24
• Fórmula: C₁₂H₁₃FN₂O₉
• Color/Forma: Off-White to Pale Yellow Solid
• SMILES: O=[N+]([O-])c1ccc(O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2F)c([N+](=O)[O-])c1