9-(3,5-Di-O-phosphono-β-D-arabinofuranosyl)-2-fluoro-9H-purin-6-amine

CAS: 548774-53-4

Ref. TR-D492253

Información del producto

• Nombre: 9-(3,5-Di-O-phosphono-β-D-arabinofuranosyl)-2-fluoro-9H-purin-6-amine
• Sinónimos: 9H-Purin-6-amine, 9-(3,5-di-O-phosphono-ß-D-arabinofuranosyl)-2-fluoro-, 9-(3,5-Di-O-phosphono-ß-D-arabinofuranosyl)-2-fluoro-9H-purin-6-amine, 3'-O-Phosphono-fludarabine Phosphate, Fludarabine Phosphate EP Impurity C

Descripción

Applications 9-(3,5-Di-O-phosphono-β-D-arabinofuranosyl)-2-fluoro-9H-purin-6-amine is derived from Fludarabine (F425000), which is used as an antineoplastic.
References Brockman, R.W., et al.: Biochem. Pharmacol., 26, 2193 (1977), Brockman, R.W., et al.: Cancer Res., 40, 3610 (1980), Chun, H.G., et al.: Cancer Treat. Rep., 70, 1225 (1986), Warrell, R.P., et al.: J. Clin. Oncol., 4, 74 (1986)

• Marca: TRC

Propiedades químicas

• Peso molecular: 445.19
• Fórmula: C₁₀H₁₄FN₅O₁₀P₂
• Color/Forma: Neat
• InChI: InChI=1S/C10H14FN5O10P2/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-5(17)6(26-28(21,22)23)3(25-9)1-24-27(18,19)20/h2-3,5-6,9,17H,1H2,(H2,12,14,15)(H2,18,19,20)(H2,21,22,23)/t3-,5+,6-,9-/m1/s1
• Clave InChI: InChIKey=FWZDRSVQWVESFS-FTWQFJAYSA-N
• SMILES: Nc1nc(F)nc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O)[C@@H](OP(=O)(O)O)[C@@H]1O