5-​(2,​4-​Dichlorophenyl)​-​N-​[4-​(3-​methyl-​1,​2,​4-​triazolo[3,​4-​b]​[1,​3,​4]​thiadiazol-​6-​yl)​phenyl]​-2-​furancarboxamide

CAS: 701253-62-5

Ref. TR-D677890

Información del producto

• Nombre: 5-​(2,​4-​Dichlorophenyl)​-​N-​[4-​(3-​methyl-​1,​2,​4-​triazolo[3,​4-​b]​[1,​3,​4]​thiadiazol-​6-​yl)​phenyl]​-2-​furancarboxamide
• Sinónimos: PTPN11, 5-(2,4-Dichlorophenyl)-N-(4-(3-methyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl)phenyl)furan-2-carboxamide
• Marca: TRC

Descripción

Applications 5-​(2,​4-​Dichlorophenyl)​-​N-​[4-​(3-​methyl-​1,​2,​4-​triazolo[3,​4-​b]​[1,​3,​4]​thiadiazol-​6-​yl)​phenyl]​-2-​furancarboxamide is used as HePTP inhibitor for treating leukemia, pre-leukemic conditions, and myelodysplastic syndrome and their screening methods.
References Mustelin, T., et al.: U.S. Pat. Appl. Publ. 27pp. (2009)

Propiedades químicas

• Peso molecular: 470.331
• Fórmula: C₂₁H₁₃Cl₂N₅O₂S
• Color/Forma: Neat
• InChI: InChI=1S/C21H13Cl2N5O2S/c1-11-25-26-21-28(11)27-20(31-21)12-2-5-14(6-3-12)24-19(29)18-9-8-17(30-18)15-7-4-13(22)10-16(15)23/h2-10H,1H3,(H,24,29)
• Clave InChI: InChIKey=YJOYTQQCKRNIPB-UHFFFAOYSA-N
• SMILES: Cc1nnc2sc(-c3ccc(NC(=O)c4ccc(-c5ccc(Cl)cc5Cl)o4)cc3)nn12