(S)-Efavirenz N-β-D-Glucuronide Methyl Ester

Ref. TR-E425065

Información del producto

• Nombre: (S)-Efavirenz N-β-D-Glucuronide Methyl Ester
• Sinónimos: methyl (2S,3S,4S,5R,6R)-6-[(4S)-6-chloro-4-(2-cyclopropylethynyl)-2-oxo-4-(trifluoromethyl)-3,1-benzoxazin-1-yl]-3,4,5-trihydroxyoxane-2-carboxylate
• Marca: TRC
• Descripción: Applications (S)-Efaveirenz N-β-Glucoronide-Methyl Ester is an intermediate in the synthesis of (S)-Efavirenz N-β-D-Glucuronide, the N-glucuronide derivative of (S)-Efavirenz (E425000); a nonnucleoside HIV-1 reverse transcriptase inhibitor. Antiviral.References Young, S.D., et al.: Antimicrob. Ag. Chemother., 39, 2602 (1995)

Propiedades químicas

• Peso molecular: 505.826
• Fórmula: C₂₁H₁₉ClF₃NO₈
• Color/Forma: Neat
• InChI: InChI=1S/C21H19ClF3NO8/c1-32-18(30)16-14(28)13(27)15(29)17(33-16)26-12-5-4-10(22)8-11(12)20(21(23,24)25,34-19(26)31)7-6-9-2-3-9/h4-5,8-9,13-17,27-29H,2-3H2,1H3/t13-,14-,15+,16-,17+,20-/m0/s1
• SMILES: COC(=O)[C@H]1O[C@@H](N2C(=O)O[C@](C#CC3CC3)(C(F)(F)F)c3cc(Cl)ccc32)[C@H](O)[C@@H](O)[C@@H]1O