Empagliflozin R/S-Furanose

CAS: 1620758-31-7 1620758-32-8

Ref. TR-E521560

Información del producto

• Nombre: Empagliflozin R/S-Furanose
• Sinónimos: (3R,4R,5R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-5-((R)-1,2-dihydroxyethyl)tetrahydrofuran-3,4-diol, (1R)-1,4-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol and (1S)-1,4-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol Mixture

Descripción

Applications Empagliflozin R/S-Furanose is a mixture of R and S isomers of Empagliflozin Furanose. Both are byproducts in the synthesis of Empagliflozin drug (E521510), which is potent and selective inhibitor of sodium glucose co-transporter-2 (SGLT-2).
References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012); Wang, X., et al.: Org. Lett., 16, 4090 (2014);

• Marca: TRC

Propiedades químicas

• Peso molecular: 450.909
• Fórmula: C₂₃H₂₇ClO₇
• Color/Forma: Neat
• InChI: InChI=1S/C23H27ClO7/c24-18-6-3-14(22-20(27)21(28)23(31-22)19(26)11-25)10-15(18)9-13-1-4-16(5-2-13)30-17-7-8-29-12-17/h1-6,10,17,19-23,25-28H,7-9,11-12H2/t17-,19+,20+,21+,22?,23+/m0/s1
• Clave InChI: InChIKey=RAQUDPJZAZMKRD-OMIXLWJZSA-N
• SMILES: OC[C@@H](O)[C@H]1OC(c2ccc(Cl)c(Cc3ccc(O[C@H]4CCOC4)cc3)c2)[C@H](O)[C@H]1O