Epirubicinol (Mixture of Diastereomers)

CAS: 76155-56-1

Ref. TR-E588655

Información del producto

• Nombre: Epirubicinol (Mixture of Diastereomers)
• Sinónimos: 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-a-L-arabino-hexopyranosyl)oxy]-8-[(1S)-1,2-dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-, 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-a-L-arabino-hexopyranosyl)oxy]-8-(1,2-dihydroxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, [8S-[8a,8(R*),10a]]-, (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-a-L-arabino-hexopyranosyl)oxy]-8-[(1S)-1,2-dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione, 4'-Epiadriamycinol, Epidoxorubicinol, Epirubicinol

Descripción

Applications A metabolite of Epirubicin, a neoplasm inhibitor.
References Salvatorelli, E., et al.: J. Biol. Chem., 281, 10990 (2006), Salvatorelli, E., et al.: J. Pharmacol. Exper. Ther., 320, 790 (2007), Efferth, T., et al.: Clin. Cancer Res., 14, 2405 (2008),

• Marca: TRC

Propiedades químicas

• Peso molecular: 545.54
• Fórmula: C₂₇H₃₁NO₁₁
• Color/Forma: Neat
• InChI: InChI=1S/C27H31NO11/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34/h3-5,10,13,15-17,22,29-31,33,35-36H,6-9,28H2,1-2H3/t10-,13-,15-,16-,17-,22-,27-/m0/s1
• Clave InChI: InChIKey=NKZRZOVSJNSBFR-QXAZHNFISA-N
• SMILES: COc1cccc2c1C(=O)c1c(O)c3c(c(O)c1C2=O)C[C@@](O)([C@@H](O)CO)C[C@@H]3O[C@H]1C[C@H](N)[C@@H](O)[C@H](C)O1