Eplerenone 7-Carboxylic Acid

CAS: 209253-82-7

Ref. TR-E588785

Información del producto

• Nombre: Eplerenone 7-Carboxylic Acid
• Sinónimos: Eplerenone EP Impurity D,Pregn-4-ene-7,21-dicarboxylic acid, 9,11-epoxy-17-hydroxy-3-oxo-, γ-lactone, (7α,11α,17α)-, (7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic acid γ-lactone, 9,11α-Epoxy-7α-carboxy-3-oxo-17α-pregn-4-ene-21,17-carbolactone, 7α-Carboxy-9,11α-epoxy-3-oxo-17α-pregn-4-ene-21,17-carbolactone, (2'R)-9,11α-Epoxy-3,5'-dioxo-4',5'-dihydro-3'H-spiro[androst-4-ene-17,2'-furan]-7α-carboxylic acid, O-Demethyleplerenone, 9,11-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid gamma-Lactone
• Marca: TRC
• Descripción: Applications Eplerenone 7-Carboxylic Acid is an impurity of Eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),

Propiedades químicas

• Peso molecular: 400.46
• Fórmula: C₂₃H₂₈O₆
• Color/Forma: Off-White To Light Yellow
• InChI: InChI=1S/C23H28O6/c1-20-6-3-13(24)9-12(20)10-14(19(26)27)18-15-4-7-22(8-5-17(25)29-22)21(15,2)11-16-23(18,20)28-16/h9,14-16,18H,3-8,10-11H2,1-2H3,(H,26,27)/t14-,15+,16-,18+,20+,21+,22-,23-/m1/s1