(7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester
CAS: 192704-82-8
Ref. TR-E589325
1mg | 293,00 € | ||
10mg | 1.981,00 € |
Información del producto
- Pregn-4-ene-7,21-dicarboxylic acid
- 11,12-epoxy-17-hydroxy-3-oxo-
- 21,17-lactone
- 7-methyl ester
- (7a,11a,12a,17a)-
- Pregn-4-ene-7,21-dicarboxylic acid
- 11,12-epoxy-17-hydroxy-3-oxo-
- ?-lactone
- methyl ester
- (7a,11a,12a,17a)- (9CI)
- Ver más sinónimos
- Spiro[11,12-epoxy-17H-cyclopenta[a]phenanthrene-17,2'(3'H)-furan]
- pregn-4-ene-7,21-dicarboxylic acid deriv.
- 11a,12a-Epoxy-7a-(methoxycarbonyl)-3-oxo-17a-pregn-4-ene-21,17-carbolactone
- 9a,11a-Deepoxy-11a,12a-epoxyeplerenone
- (7Alpha,11Alpha,12Alpha,17Alpha)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone
- Methyl Ester
Applications (7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester is an impurity of eplerenone (E588775). Eplerenone is a selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
References de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),
Propiedades químicas
Consulta técnica sobre: TR-E589325 (7α,11α,12α,17α)-11,12-Epoxy-17-hydroxy-3-oxo-pregn-4-ene-7,21-dicarboxylic Acid Lactone, Methyl Ester
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