Ergovaline

CAS: 2873-38-3

Ref. TR-E600050

Información del producto

• Nombre: Ergovaline
• Sinónimos: (5'α)-12'-Hydroxy-2'-methyl-5'-(1-methylethyl)-ergotaman-3',6',18-trione, 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotaman-3',6',18-trione deriv., 4,6,6a,7,8,9-hexahydro-7-methyl-N-(octahydro-10b-hydroxy-5-isopropyl-2-methyl-3,6-dioxo-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)- indolo[4,3-fg]quinoline-9-carboxamide, (5'alpha)-9,10-Dihydro-12'-hydroxy-2'-methyl-5'-(1-methylethyl)ergotaman-3',6',18-trione, (5′α)-12′-Hydroxy-2′-methyl-5′-(1-methylethyl)ergotaman-3′,6′,18-trione, 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotaman-3′,6′,18-trione deriv., Ergotaman-3′,6′,18-trione, 12′-hydroxy-2′-methyl-5′-(1-methylethyl)-, (5′α)-, Indolo[4,3-fg]quinoline, ergotaman-3′,6′,18-trione deriv., Indolo[4,3-fg]quinoline-9-carboxamide, 4,6,6a,7,8,9-hexahydro-7-methyl-N-(octahydro-10b-hydroxy-5-isopropyl-2-methyl-3,6-dioxo-8H-oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl)-
• CAS: 2873-38-3

Descripción

Stability Unstable in solution
Applications Ergovaline is an ergopetine alkaloid commonly found in endophyte-infected species of tall grass fescue. Ergovaline is known to cause tall fescue toxicosis and is toxic to cattle feeding on the infected grass as it inhibits vesicular glutamate transporter activity in cow cerebral synatic vesicles.
References Xue, Y., et al.: J. Dairy. Sci., 94, 3331 (2011); Najafabdi, A.S., et al.: Res. Pharm. Sci., 5, 135 (2010); Foote, A.P., et al.: J. Animial. Sci., 89, 2944 (2011); Reed, K.F., et al.: Animal. Prod. Sci., 51, 1098 (2011);

• Marca: TRC

Propiedades químicas

• Peso molecular: 533.6187
• Fórmula: C₂₉H₃₅N₅O₅
• Color/Forma: Light Beige to Dark Brown Solid
• InChI: InChI=1S/C29H35N5O5/c1-15(2)24-26(36)33-10-6-9-22(33)29(38)34(24)27(37)28(3,39-29)31-25(35)17-11-19-18-7-5-8-20-23(18)16(13-30-20)12-21(19)32(4)14-17/h5,7-8,11,13,15,17,21-22,24,30,38H,6,9-10,12,14H2,1-4H3,(H,31,35)/t17-,21-,22+,24+,28-,29+/m1/s1
• Clave InChI: InChIKey=BGHDUTQZGWOQIA-VQSKNWBGSA-N
• SMILES: CC(C)[C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@@](C)(NC(=O)[C@@H]3C=C4c5cccc6[nH]cc(c56)C[C@H]4N(C)C3)C(=O)N12