9-Fluoro-11Beta,17,21-trihydroxy-16Beta-methylpregn-4-ene-3,20-dione 17-Propionate

CAS: 25122-39-8

Ref. TR-F599220

Información del producto

• Nombre: 9-Fluoro-11Beta,17,21-trihydroxy-16Beta-methylpregn-4-ene-3,20-dione 17-Propionate
• Sinónimos: [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-yl] propanoate
• Marca: TRC

Descripción

Applications 9-Fluoro-11β,17,21-trihydroxy-16β-methylpregn-4-ene-3,20-dione 17-Propionate is an intermediate used in the synthesis of 21-Chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregn-4-ene-3,20-dione 17-Propionate (C366305), which is an impurity of Clobetasol 17-Propionate (C583500), an topical corticosteroid with anti-inflammatory properties.
References Olsen, E.A., et al.: J. Am. Acad. Dermatol., 15, 246 (1986)

Propiedades químicas

• Peso molecular: 450.54
• Fórmula: C₂₅H₃₅FO₆
• Color/Forma: Neat
• InChI: InChI=1S/C25H35FO6/c1-5-21(31)32-25(20(30)13-27)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,26)19(29)12-23(18,25)4/h11,14,17-19,27,29H,5-10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1
• Clave InChI: InChIKey=SBXHECDIRFBCAY-XGQKBEPLSA-N
• SMILES: CCC(=O)O[C@]1(C(=O)CO)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C