Fursultiamine

CAS: 804-30-8

Ref. TR-F865235

Información del producto

• Nombre: Fursultiamine
• Sinónimos: Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]-, Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]- (6CI,8CI), Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]- (9CI), N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]formamide, Adventan, Alinamin F, Diteftin, Fursultiamin, Judolor, Linamin, N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]formamide, Retar B1, TTFD, Tetrahydrofurfuryl thiamine disulfide, Thiamin tetrahydrofurfuryl disulfide, Thiamine tetrahydrofurfuryl disulfide, Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]-, Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-buten-1-yl]-, Formamide, N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-, N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-{(1Z)-4-hydroxy-1-methyl-2-[(tetrahydrofuran-2-ylmethyl)disulfanyl]but-1-en-1-yl}formamide, N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-{5-hydroxy-3-[(tetrahydrofuran-2-ylmethyl)disulfanyl]pent-2-en-2-yl}formamide, Retar B₁

Descripción

Applications Fursultiamine is an oral source of thiamine, used in comparative pharmacokinectic analysis of thiamine and it’s phosphorylated metabolites administered as multivitamin preparations, identification of drug candidate against prostate cancer from aspect of somatic cell reprogramming, therapeutic tool in number of human neurological diseases.
References Park, W., et al.: Clin. Ther., 38, 2277 (2016); Kosaka, T., et al.: Cancer Sci., 104, 1017 (2013); Lonsdale, D., et al.: Med. Sci. Monit., 10, 199 (2004)

• Marca: TRC

Propiedades químicas

• Peso molecular: 398.54
• Fórmula: C₁₇H₂₆N₄O₃S₂
• Color/Forma: Neat
• InChI: InChI=1S/C17H26N4O3S2/c1-12(16(5-6-22)26-25-10-15-4-3-7-24-15)21(11-23)9-14-8-19-13(2)20-17(14)18/h8,11,15,22H,3-7,9-10H2,1-2H3,(H2,18,19,20)
• Clave InChI: InChIKey=JTLXCMOFVBXEKD-FOWTUZBSSA-N
• SMILES: C/C(=C(/CCO)SSCC1CCCO1)N(C=O)Cc1cnc(C)[nH]c1=N