Glufosfamide

CAS: 132682-98-5

Ref. TR-G596880

Información del producto

• Nombre: Glufosfamide
• Sinónimos: D 19575, Glucosylifosfamide Mustard, 1-[N,N'-bis(2-Chloroethyl)phosphorodiamidate] β-D-Glucopyranose, (2S,3R,4S,5S,6R)-2-Bis(2-chloroethylamino)phosphoryloxy-6-(hydroxymethyl)oxane-3,4,5-triol, 1-O-{bis[(2-chloroethyl)amino]phosphoryl}-beta-D-glucopyranose, Glucosylifosfamide mustard, Glufosfamide,B-D-Glucopyranose, 1-(N,N'-Bis(2-Chloroethyl)Phosphorodiamidate)-, β-<span class="text-smallcaps">D</span>-Glucopyranose, 1-[N,N′-bis(2-chloroethyl)phosphorodiamidate], β-D-Glucopyranose, 1-[N,N′-bis(2-chloroethyl)phosphorodiamidate]

Descripción

Applications Glufosfamide is an alkylating cytotoxic agent with increased antitumor selectivity and active transmembrane transport mechanism, that belongs to the oxazaphosphorine class. It is an attractive new agent for cancer therapy in humans.
References Pohl, J., et al.: Cancer Chemother. Pharmacol., 35, 364 (1995); Mazur, L., et al.: Anticancer Drugs, 22, 488 (2011);

• Marca: TRC

Propiedades químicas

• Peso molecular: 383.163
• Fórmula: C₁₀H₂₁Cl₂N₂O₇P
• Color/Forma: Neat
• InChI: InChI=1S/C10H21Cl2N2O7P/c11-1-3-13-22(19,14-4-2-12)21-10-9(18)8(17)7(16)6(5-15)20-10/h6-10,15-18H,1-5H2,(H2,13,14,19)/t6-,7-,8+,9-,10+/m1/s1
• Clave InChI: InChIKey=PSVUJBVBCOISSP-SPFKKGSWSA-N
• SMILES: O=P(NCCCl)(NCCCl)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O