GW0742 Sulfoxide

Ref. TR-G930010

Información del producto

• Nombre: GW0742 Sulfoxide
• Sinónimos: 2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfinyl]-2-methylphenoxy]acetic acid
• Marca: TRC
• Descripción: Stability Light SensitiveApplications GW0742 Sulfoxide is derived from GW0742 (G930000), which is small molecule agonist of the human Peroxisome Proliferator-Activated Receptor δ (PPAR δ). It shows EC50 of 1.1 nM against PPAR δ with 100-fold selectivity over the other human subtypes.References Sznaidman, M.L., et al.: Bioorganic and Medicinal Chemistry Letters, 13, 1517 (2003)

Propiedades químicas

• Peso molecular: 487.49
• Fórmula: C₂₁H₁₇F₄NO₄S₂
• Color/Forma: Neat
• InChI: InChI=1S/C21H17F4NO4S2/c1-11-7-14(4-6-17(11)30-9-19(27)28)32(29)10-18-12(2)26-20(31-18)13-3-5-15(16(22)8-13)21(23,24)25/h3-8H,9-10H2,1-2H3,(H,27,28)
• Clave InChI: InChIKey=MQEOGFMEZMYOQJ-UHFFFAOYSA-N
• SMILES: Cc1cc(S(=O)Cc2sc(-c3ccc(C(F)(F)F)c(F)c3)nc2C)ccc1OCC(=O)O