GW 4064

CAS: 278779-30-9

Ref. TR-G931000

Información del producto

• Nombre: GW 4064
• Sinónimos: 3-[(E)-2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid, 3-(2,6-Dichlorophenyl)-4-(3'-carboxy-2-chlorostilben-4-yl)oxymethyl-5-isopropylisoxazole, 3-[(E)-2-(2-chloro-4-{[3-(2,6-dichlorophenyl)-5-(1-methylethyl)isoxazol-4-yl]methoxy}phenyl)ethenyl]benzoic acid, 3-[2-[2-Chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]benzoic acid, Benzoic acid, 3-[2-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methoxy]phenyl]ethenyl]-
• CAS: 278779-30-9

Descripción

Applications A novel nonsteroidal FXR nuclear receptor agonist.
References Makishima, M., et al.: Science, 284, 1362 (1999), Wang, H., et al.: Mol. Cell, 3, 543 (1999), Zhang, Y., et al.: J. Biol. Chem., 276, 43018 (2001), Carlton, V.E., et al.: Nat. Genet., 34, 91 (2003),

• Marca: TRC

Propiedades químicas

• Peso molecular: 542.84
• Fórmula: C₂₈H₂₂Cl₃NO₄
• Color/Forma: Neat
• InChI: InChI=1S/C28H22Cl3NO4/c1-16(2)27-21(26(32-36-27)25-22(29)7-4-8-23(25)30)15-35-20-12-11-18(24(31)14-20)10-9-17-5-3-6-19(13-17)28(33)34/h3-14,16H,15H2,1-2H3,(H,33,34)/b10-9+
• Clave InChI: InChIKey=BYTNEISLBIENSA-MDZDMXLPSA-N
• SMILES: CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(/C=C/c2cccc(C(=O)O)c2)c(Cl)c1