Hemiacetorphan

CAS: 124735-06-4

Ref. TR-H235105

Información del producto

• Nombre: Hemiacetorphan
• Sinónimos: N-[2-[(Acetylthio)methyl]-1-oxo-3-phenylpropyl]glycine, Glycine, N-[2-[(acetylthio)methyl]-1-oxo-3-phenylpropyl]-, (+/-)-, S-Acetylthiorphan, [[(2RS)-2-[(Acetylsulfanyl)methyl]-3-phenylpropanoyl]amino]acetic Acid, Glycine, N-(2-((acetylthio)methyl)-1-oxo-3-phenylpropyl)-, (+-)-, N-(2-((Acetylthio)methyl)-1-oxo-3-phenylpropyl)glycine, S-Acetylthiophan, N-[3-(acetylsulfanyl)-2-benzylpropanoyl]glycine
• CAS: 124735-06-4

Descripción

Applications Hemiacetorphan is an impurity of Racecadotril (R070600), which is antidiarrheal, enkephalinase inhibitor, and also capable of reducing the amount of water and electrolytes into the intestine.
References Cezard, J., et al.: Gastroenterol., 120, 799 (2001), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Lakshmana, P., et al.: J. Pharm. Res., 8, 39 (2009),

• Marca: TRC

Propiedades químicas

• Peso molecular: 295.35
• Fórmula: C₁₄H₁₇NO₄S
• Color/Forma: White to Off-White Solid
• InChI: InChI=1S/C14H17NO4S/c1-10(16)20-9-12(14(19)15-8-13(17)18)7-11-5-3-2-4-6-11/h2-6,12H,7-9H2,1H3,(H,15,19)(H,17,18)
• Clave InChI: InChIKey=DCMKACHZOPSUHN-UHFFFAOYSA-N
• SMILES: CC(=O)SCC(Cc1ccccc1)C(=O)NCC(=O)O