Homatropine Methylbromide

CAS: 80-49-9

Ref. TR-H459225

Información del producto

• Nombre: Homatropine Methylbromide
• Sinónimos: (1R,3r,5S)-3-[[(2RS)-2-Hydroxy-2-phenylacetyl]oxy]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide, 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropanium, 3α-hydroxy-8-methyl-, bromide, mandelate, 1αH,5αH-Tropanium, 3α-hydroxy-8-methyl-, bromide, mandelate, 8-Azoniabicyclo[3.2.1]octane, 3-[(2-hydroxy-2-phenylacetyl)oxy]-8,8-dimethyl-, bromide (1:1), (3-endo)-, 8-Azoniabicyclo[3.2.1]octane, 3-[(hydroxyphenylacetyl)oxy]-8,8-dimethyl-, bromide, endo-, 8-Methylhomatropinium bromide, Arkitropin, Camatropine, Esopin, Helbatropin, Homapin, Homatrocel, Homatromide, Homatropil, Homatropine methobromide, Homatropinmethylbromid, Homolone, Malcotran, Mesopin, Methatropin, Methatropine, Methylbromure d'homatropine, Methylhomatropine bromide, Methylhomatropine hydrobromide, Methylhomatropinium bromide, Metilbromuro De Homatropina, Novatrin, Novatrine, Novatropin, Novatropine, Nsc 34399, Sed-Tems, Sethyl, Tropinium methobromide mandelate

Descripción

Applications Homatropine methylbromide or Methylhomatropine bromide is a quaternary ammonium salt of methylhomatropine. Methylhomatropine is a peripherally acting anticholinergic medication that inhibits muscarinic acetylcholine receptors and thus the parasympathetic nervous system. Methylhomatropine does not cross the blood-brain barrier. Methylhomatropine is used, in addition to papaverine, as component of mild drugs that help "flush" the bile.
References Schroeder, F., et al.: Biochemistry, 34, 11919 (1995); Krungkrai, J., et al.: Bioorg. Med. Chem., 15, 483 (2005); Zeng, B., et al.: Microbiology, 152, 2355 (2006); Hongmanee, P., et al.: Antimicrob. Agents Chemother., 51, 1105 (2007);

• Marca: TRC

Propiedades químicas

• Peso molecular: 370.28
• Fórmula: C₁₇H₂₄NO₃·Br
• Color/Forma: White To Off-White
• InChI: InChI=1S/C17H24NO3.BrH/c1-18(2)13-8-9-14(18)11-15(10-13)21-17(20)16(19)12-6-4-3-5-7-12;/h3-7,13-16,19H,8-11H2,1-2H3;1H/q+1;/p-1/t13-,14+,15+,16-;/m1./s1
• Clave InChI: InChIKey=NAABJORKYJMVLT-UHFFFAOYSA-N
• SMILES: CBr.CN1C2CCC1CC(OC(=O)C(O)c1ccccc1)C2