m-Hydroxycocaine

CAS: 71387-58-1

Ref. TR-H825443

Información del producto

• Nombre: m-Hydroxycocaine
• Sinónimos: (1R,2R,3S,5S)-3-[(3-Hydroxybenzoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester
• CAS: 71387-58-1

Descripción

Applications m-Hydroxycocaine is a metabolite of Cocaine (HCl: C633500), a vasoconstrictive agent that is highly addictive and has high potential for abuse. The mechanism by which Cocaine induces dependence is unknown, but it is hypothesized that it works by blocking the dopamine transporter, increasing the amount of free dopamine in the brain.
References Carrera, M., et al.: Nature, 378, 727 (1995); Moore, T., et al.: Am. J. Obst. Gyne., 155, 883 (1986); Volkow, N., et al.: Nature, 386, 827 (1997)

• Marca: TRC

Propiedades químicas

• Peso molecular: 319.35
• Fórmula: C₁₇H₂₁NO₅
• Color/Forma: White to Off-White Solid
• InChI: InChI=1S/C17H21NO5/c1-18-11-6-7-13(18)15(17(21)22-2)14(9-11)23-16(20)10-4-3-5-12(19)8-10/h3-5,8,11,13-15,19H,6-7,9H2,1-2H3/t11-,13+,14-,15+/m0/s1
• Clave InChI: InChIKey=IQXBUEUAOWARGT-PMOUVXMZSA-N
• SMILES: COC(=O)[C@H]1[C@@H](OC(=O)c2cccc(O)c2)C[C@@H]2CC[C@H]1N2C