p-Hydroxycocaine Hydrochloride

CAS: 197771-77-0

Ref. TR-H825445

Información del producto

• Nombre: p-Hydroxycocaine Hydrochloride
• Sinónimos: (1R,2R,3S,5S)-3-[(4-Hydroxybenzoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester Hydrochloride, [1R-(exo,exo)]-3-[(4-Hydroxybenzoyl)oxy]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic Acid Methyl Ester Hydrochloride, 4'-Hydroxybenzoylecgonine Methyl Ester Hydrochloride, 4'-Hydroxycocaine Hydrochloride
• CAS: 197771-77-0

Descripción

Applications: p-Hydroxycocaine is a metabolite of Cocaine (HCl: C633500), a vasoconstrictive agent that is highly addictive and has high potential for abuse. The mechanism by which Cocaine induces dependence is unknown, but it is hypothesized that it works by blocking the dopamine transporter, increasing the amount of free dopamine in the brain.
References Carrera, M., et al.: Nature, 378, 727 (1995); Moore, T., et al.: Am. J. Obst. Gyne., 155, 883 (1986); Volkow, N., et al.: Nature, 386, 827 (1997)

• Marca: TRC

Propiedades químicas

• Peso molecular: 355.81
• Fórmula: C₁₇H₂₁NO₅•HCl
• Color/Forma: Neat
• InChI: InChI=1S/C17H21NO5.ClH/c1-18-11-5-8-13(18)15(17(21)22-2)14(9-11)23-16(20)10-3-6-12(19)7-4-10;/h3-4,6-7,11,13-15,19H,5,8-9H2,1-2H3;1H/t11-,13+,14-,15+;/m0./s1
• Clave InChI: InChIKey=AOSQZYJCIGWNGT-HLYGUNNVSA-N
• SMILES: COC(=O)[C@H]1[C@@H](OC(=O)c2ccc(O)cc2)C[C@@H]2CC[C@H]1N2C.Cl