(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer)
CAS: 112093-28-4
Ref. TR-H938500
1mg | 499,00 € | ||
5mg | 2.064,00 € | ||
500µg | 285,00 € |
Información del producto
- 4-[(Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol
- (Z)-4-Hydroxy-N-desmethyl Tamoxifen
- (Z)-Endoxifen
- 4-Hydroxy-N-desmethyltamoxifen
- 4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol
- 4-[(1Z)-1-{4-[2-(methylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl]phenol
- N-Desmethyl-4-hydroxytamoxifen
- Phenol, 4-[(1Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-
- Phenol, 4-[(1Z)-1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]-
- Phenol, 4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]-, (Z)-
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Stability Light Sensitive, Temperature Sensitive
Applications A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Furr, B., et al.: Pharmacol. Ther., 25, 127 (1984), Leonessa, F., et al.: Cancer Res., 54, 441 (1994), Stearns, V., et al.: Lancet, 360, 1851 (2002), Rae, J., et al.: Pharmacogenetics, 13, 501 (2003),
Propiedades químicas
Consulta técnica sobre: TR-H938500 (Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer)
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