7-Hydroxy Methotrexate Ammonium Salt

CAS: 5939-37-7

Ref. TR-H945926

Información del producto

• Nombre: 7-Hydroxy Methotrexate Ammonium Salt
• Sinónimos: Ammonium (S)-4-carboxy-2-(4-(((2,4-diamino-7-hydroxypteridin-6-yl)methyl)(methyl)amino)benzamido)butanoate, 7-Hydroxymethotrexate, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2,4-diamino-1,7-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-Glutamic acid, N-[4-[[(2,4-diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-, Glutamic acid, N-[p-[[(2,4-diamino-7-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]-, Glutamic acid, N-[p-[[(2,4-diamino-7-hydroxy-6-pteridinyl)methyl]methylamino]benzoyl]-, <span class="text-smallcaps">L</span>-(+)-, N-[(4-{[(2,4-diamino-7-oxo-7,8-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]-L-glutamic acid, N-[(4-{[(2,4-diamino-7-oxo-7,8-dihydropteridin-6-yl)methyl](methyl)amino}phenyl)carbonyl]glutamic acid, N-[4-[[(2,4-Diamino-7,8-dihydro-7-oxo-6-pteridinyl)methyl]methylamino]benzoyl]-<span class="text-smallcaps">L</span>-glutamic acid, NSC 380962

Descripción

Applications 7-Hydroxy Methotrexate Ammonium Salt is a metabolite of Methotrexate (M260675), which is used as an antineoplastic and antirheumatic.
References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),

• Marca: TRC

Propiedades químicas

• Peso molecular: 487.47
• Fórmula: C₂₀H₂₅N₉O₆
• Color/Forma: Neat
• InChI: InChI=1S/C20H22N8O6.H3N/c1-28(8-12-18(32)26-16-14(23-12)15(21)25-20(22)27-16)10-4-2-9(3-5-10)17(31)24-11(19(33)34)6-7-13(29)30;/h2-5,11H,6-8H2,1H3,(H,24,31)(H,29,30)(H,33,34)(H5,21,22,25,26,27,32);1H3/t11-;/m0./s1
• Clave InChI: InChIKey=JLDHVBVOYCTWSZ-MERQFXBCSA-N