5-Hydroxy-6-methoxy Duloxetine Sulfate

CAS: 732983-57-2

Ref. TR-H946260

Información del producto

• Nombre: 5-Hydroxy-6-methoxy Duloxetine Sulfate
• Sinónimos: 5-Hydroxy-6-methoxyduloxetine Sulfate Ester, 1-Naphthalenol, 2-methoxy-5-[(1S)-3-(methylamino)-1-(2-thienyl)propoxy]-, 1-(hydrogen sulfate), 1-Naphthalenol, 2-methoxy-5-[(1S)-3-(methylamino)-1-(2-thienyl)propoxy]-, hydrogen sulfate (ester) (9CI), 2-Methoxy-5-[(1S)-3-(methylamino)-1-(2-thienyl)propoxy]-1-naphthalenyl hydrogen sulfate, 5-Hydroxy-6-methoxyduloxetine sulfate, 5-Hydroxy-6-methoxyduloxetine sulfate ester, 2-Methoxy-5-[(1S)-3-(methylamino)-1-(thiophen-2-yl)propoxy]naphthalen-1-ol 1-(hydrogen sulfate), 2-Methoxy-5-[(1S)-3-(methylamino)-1-(2-thienyl)propoxy]-1-naphthalenol 1-(Hydrogen Sulfate), LY 581920
• CAS: 732983-57-2

Descripción

Applications 5-Hydroxy-6-methoxy Duloxetine Sulfate is a metabolite of Duloxetine (D721000), an antidepressant. A dual serotonin and norepinephrine reuptake inhibitor (SNRI). Used in treatment of stress urinary incontinence.
References Wong, D.T., et al.: Neuropsychopharmacology, 8, 23 (1993), Fuller, R.W., et al.: J. Pharmacol. Exp. Ther., 269, 132 (1994), Sharma, A., et al.: J. Clin. Pharmacol., 40, 161 (2000)

• Marca: TRC

Propiedades químicas

• Peso molecular: 423.50
• Fórmula: C₁₉H₂₁NO₆S₂
• Color/Forma: Neat
• InChI: InChI=1S/C19H21NO6S2/c1-20-11-10-16(18-7-4-12-27-18)25-15-6-3-5-14-13(15)8-9-17(24-2)19(14)26-28(21,22)23/h3-9,12,16,20H,10-11H2,1-2H3,(H,21,22,23)/t16-/m0/s1
• Clave InChI: InChIKey=XYZBSFYKOKLCKI-INIZCTEOSA-N
• SMILES: CNCC[C@H](Oc1cccc2c(OS(=O)(=O)O)c(OC)ccc12)c1cccs1