Hydroxy Ritonavir

CAS: 176655-56-4

Ref. TR-H953390

Información del producto

• Nombre: Hydroxy Ritonavir
• Sinónimos: 2,7,10,12-Tetraazatridecanoic acid, 4-hydroxy-13-[2-(1-hydroxy-1-methylethyl)-4-thiazolyl]-12-methyl-9-(1-methylethyl)-8,11-dioxo-3,6-bis(phenylmethyl)-, 5-thiazolylmethyl ester, (3S,4S,6S,9S)-, 2,4,7,12-Tetraazatridecan-13-oic acid, 10-hydroxy-1-[2-(1-hydroxy-1-methylethyl)-4-thiazolyl]-2-methyl-5-(1-methylethyl)-3,6-dioxo-8,11-bis(phenylmethyl)-, 5-thiazolylmethyl ester, [5S-(5R*,8R*,10R*,11R*)]-, Thiazol-5-ylmethyl [(1S,2S,4S)-1-Benzyl-2-hydroxy-4-[[(2S)-2-[[[[2-(1-hydroxy-1-methylethyl)thiazol-4-yl]methyl]methyl-carbamoyl]amino]-3-methylbutanoyl]amino]-5-phenylpentyl]carbamate, Ritonavir Imp. E (EP)

Descripción

Impurity Ritonavir EP Impurity E
Applications Hydroxy Ritonavir (Ritonavir EP Impurity E) is a metabolite of Ritonavir (R535000), HIV-1 protease inhibitor. It is a COVID19-related research product.
References Eagling, V., et al.: Br. J. Clin. Pharmacol., 48, 543 (1999), Eagling, V., et al.: Xenobiotica, 32, 1 (2002), Meaden, E., et al.: J. Antimicrob. Chemother., 50, 583 (2002), Treijtel, N., et al.: Drug Metab. Dispos., 33, 1325 (2005),

• Marca: TRC

Propiedades químicas

• Peso molecular: 736.94
• Fórmula: C₃₇H₄₈N₆O₆S₂
• Color/Forma: Neat
• InChI: InChI=1S/C37H48N6O6S2/c1-24(2)32(42-35(46)43(5)20-28-22-50-34(40-28)37(3,4)48)33(45)39-27(16-25-12-8-6-9-13-25)18-31(44)30(17-26-14-10-7-11-15-26)41-36(47)49-21-29-19-38-23-51-29/h6-15,19,22-24,27,30-32,44,48H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t27-,30-,31-,32-/m0/s1
• Clave InChI: InChIKey=CLEDZMPJHBBTNZ-QJANCWQKSA-N
• SMILES: CC(C)[C@H](NC(=O)N(C)Cc1csc(C(C)(C)O)n1)C(=O)N[C@@H](Cc1ccccc1)C[C@H](O)[C@H](Cc1ccccc1)NC(=O)OCc1cncs1