Hydroxythiohomo Sildenafil

CAS: 479073-82-0

Ref. TR-H963150

Información del producto

• Nombre: Hydroxythiohomo Sildenafil
• Sinónimos: 7H-Pyrazolo[4,3-d]pyrimidine-7-thione, 5-[2-ethoxy-5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-, 1-Piperazineethanol, 4-[[3-(4,7-dihydro-1-methyl-3-propyl-7-thioxo-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]- (9CI), 5-(2-ethoxy-5-(4-(2-hydroxyethyl)piperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidine-7(6H)-thione, Hydroxythiohomosildenafil, Thiohydroxyhomosildenafil, 1-Piperazineethanol, 4-[[3-(4,7-dihydro-1-methyl-3-propyl-7-thioxo-1H-pyrazolo[4,3-d]pyrimidin-5-yl)-4-ethoxyphenyl]sulfonyl]-, 7H-Pyrazolo[4,3-d]pyrimidine-7-thione, 5-[2-ethoxy-5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-, 5-[2-Ethoxy-5-[[4-(2-hydroxyethyl)-1-piperazinyl]sulfonyl]phenyl]-1,6-dihydro-1-methyl-3-propyl-7H-pyrazolo[4,3-d]pyrimidine-7-thione

Descripción

Applications Hydroxythiohomo Sildenafil is a Sildenafil thiono analog, a novel pyrazolopyrimidinethione with PDE5 inhibiting properties.
References Koh, H.L. and Woo, S.O. 2000. Drug Saf. 23: 351-362; Seftel, A.D., 2004. Clin Cardiol. 27: I14-I19; Bednar, M.M. 2008. Curr Opin Investig Drugs. 9: 754-759.

• Marca: TRC

Propiedades químicas

• Peso molecular: 520.67
• Fórmula: C₂₃H₃₂N₆O₄S₂
• Color/Forma: Neat
• InChI: InChI=1S/C23H32N6O4S2/c1-4-6-18-20-21(27(3)26-18)23(34)25-22(24-20)17-15-16(7-8-19(17)33-5-2)35(31,32)29-11-9-28(10-12-29)13-14-30/h7-8,15,30H,4-6,9-14H2,1-3H3,(H,24,25,34)
• Clave InChI: InChIKey=XZVSAQIQEGFWQS-UHFFFAOYSA-N
• SMILES: CCCc1nn(C)c2c(=S)nc(-c3cc(S(=O)(=O)N4CCN(CCO)CC4)ccc3OCC)[nH]c12