2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic Acid (>90%)

CAS: 1809272-85-2

Ref. TR-H972788

Información del producto

• Nombre: 2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic Acid (>90%)
• Sinónimos: 4-Thiazolecarboxylic acid, 2-[(2-hydroxy-4,5-dimethoxybenzoyl)amino]- (ACI), 2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic acid (ACI), 2-(2-Hydroxy-4,5-dimethoxybenzamido)thiazole-4-carboxylic Acid, 2-(2-Hydroxy-4,5-dimethoxybenzamido)-1,3-thiazole-4carboxylic Acid

Descripción

Applications 2-[(2-Hydroxy-4,5-dimethoxybenzoyl)amino]-4-thiazolecarboxylic Acid is an impurity of Acotiamide (A190260), an acetylcholinesterase inhibitor which has been shown to stimulate gastric motility and improve gastric motility dysfunction in rats. Acotiamide Hydrochloride has also been shown to improve meal-related symptoms of functional dyspepsia.
References Masanao, K., et. al.: Eur. J. Pharmacol., 666, 218 (2011); Matsunaga, Y., et. al.: J. Pharmacol. Exp. Ther., 336, 791 (2011)

• Marca: TRC

Propiedades químicas

• Peso molecular: 324.31
• Fórmula: C₁₃H₁₂N₂O₆S
• Pureza: >90%
• Color/Forma: Neat
• InChI: InChI=1S/C13H12N2O6S/c1-20-9-3-6(8(16)4-10(9)21-2)11(17)15-13-14-7(5-22-13)12(18)19/h3-5,16H,1-2H3,(H,18,19)(H,14,15,17)
• Clave InChI: InChIKey=JVFCMPKBFPIOON-UHFFFAOYSA-N
• SMILES: CC(C)c1c(C(=O)Nc2ccccc2)c(-c2ccccc2)c(-c2ccc(F)cc2)n1CCC(O)CC(=O)CC(=O)O