1’-Hydroxy N-Trityl Medetomidine-d3

CAS: 176721-03-2

Ref. TR-H974402

Información del producto

• Nombre: 1’-Hydroxy N-Trityl Medetomidine-d3
• Sinónimos: alpha-(2,3-Dimethylphenyl)-alpha-methyl-1-(triphenylmethyl)-1H-imidazole-4-methanol-d3, 1'-Hydroxy N-Trityl Medetomidine
• CAS: 176721-03-2

Descripción

Applications 1’-Hydroxy N-Trityl Medetomidine-d3 is an intermediate in the synthesis of Dexmedetomidine-d4 L-Tartrate (d4-Major) (D299006). Dexmedetomidine-d4 L-Tartrate is the labeled salt analogue of Dexmedetomidine (D299000), an α2-Adrenergic agonist; (+)-isomer of Medetomidine; sedative; analgesic.
References Rajala, R., et al.: Eur. J. Pharm. Sci., 1, 219 (1994); Jalonen, J., et al.: Anesthesiology, 86, 331 (1997); Talke, P., et al.: Anesth. Analg., 85, 1136 (1997); Bhana, N., et al.: Drugs, 59, 263 (2000)

• Marca: TRC

Propiedades químicas

• Peso molecular: 461.612
• Fórmula: C₃₂H₂₇D₃N₂O
• Color/Forma: Neat
• InChI: InChI=1S/C32H30N2O/c1-24-14-13-21-29(25(24)2)31(3,35)30-22-34(23-33-30)32(26-15-7-4-8-16-26,27-17-9-5-10-18-27)28-19-11-6-12-20-28/h4-23,35H,1-3H3/i3D3
• Clave InChI: InChIKey=IRVSISQLIAZXEF-HPRDVNIFSA-N
• SMILES: [2H]C([2H])([2H])C(O)(c1cn(C(c2ccccc2)(c2ccccc2)c2ccccc2)cn1)c1cccc(C)c1C